PPI logo P. s. pv. tomato DC3000 P. s. pv. phaseolicola 1448A
Pto DC3000 - Plant Interaction

genome resources
home page


Genomic analyses are revealing an increasingly complex web of interactions occurring between pathogen and host gene products. Systematic characterizations of these interactions is being modeled using Gene Ontology (GO) Annotation.

Virulence factors with associated GO annotations
(click on hyperlinks for individual Pst DC3000 virulence factors to see the complete list of annotations for each)
Key to modified Gene Ontology Annotation used to describe the Pst DC3000-host interaction

Frequently Asked Questions

Pto DC3000 Hop effector proteins
hopQ1-2
hopAN1
hopAQ1
-
Hop effector proteins (not present in Pto DC3000)
avrA1
avrB1
avrB2
avrRpm1
avrRps4
avrRpt2
hopAB1
hopAR1
Harpins, pilus-associated proteins, and T3SS helpers
Toxins
coronatine
mangotoxin
phaseolotoxin
-
Pamps
flagellin
LPS
EF-Tu
-


AvrE1 (PSPTO_1377)
host cell
C
Badel, 2006
-
IDA
N benth
-
pathogenesis
P
Badel, 2006
-
IDA
N tab xanthi
-
Debroy, 2004
-
IDA
A thal Col-0
-
Badel, 2006
-
IDA
N benth
-
Badel, 2006
-
IDA
S. lyco Money maker
-
interaction with host via protein secreted by type III secretion system
P
Badel, 2006
-
IDA
N benth
-
positive regulation of growth or development of symbiont during interaction with host 
P
Badel, 2006
HopM1 Q887D0
IGI
S. lyco Money maker
-
Debroy, 2004
-
IDA
A thal Col-0
-
killing by symbiont of host cells 
P
Badel, 2006
-
IDA
N benth
-
Badel, 2006
-
IDA
N tab xanthi
-
Badel, 2006
-
IDA
S lyco Money maker
-
positive regulation by symbiont of host defense-related PCD
P
Alfano,2000
avrE (Pto PT23)
ISS
Glycine max
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Debroy, 2004
-
IDA
A thal Col-0
-
negative regulation by symbiont of host salicylic acid-mediated defense response
P
Debroy,2004
-
IGI
A thal Col-0
-


avrPto
(PSPTO_4001)
host cell plasma membrane
C
Shan, 2000
-
IDA
N tab W38
-
protein kinase binding
F
Scofield, 1996
-
IPI
S lyco Rio Grande
binds Pto
Xiang, 2008
-
IPI,IMP
A thal Col-0
binds FLs2
Xiang, 2008
-
IPI
A thal Col-0
binds EFR
Xiang, 2008
-
IPI, IMP
S lyco Money maker
binds LeFLS2
Shan,2008
-
IPI
A thal
binds BAK1
pathogenesis
P
Scofield, 1996
-
IDA
N benth
-
Ronald, 1992
-
IDA
S lyco Rio Grande 76
-
Hauck, 2003
-
IDA
A thal Col-0
-
interaction with host via protein secreted by type III secretion system
P
Schechter, 2004 
-
IDA
S lyco Money maker
-
Schechter, 2004 
-
IDA
N benth
-
positive regulation of growth or development of symbiont during interaction with host 
P
Chang, 2000
AvrPto (Pto T1)
ISS
S lyco Rio Grande 76
-
Hauck, 2003
-
-
A thal Col-0
-
positive regulation by symbiont of host defense-related PCD
P
Ronald, 1992
-
IDA
S lyco Rio Grande 76
-
negative regulation by symbiont of defense-related host callose deposition
P
Hauck, 2003
-
IDA
A thal Col-0
reduces callose deposition induced by hrcC- DC3000
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
He, 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1, MPK3, MPK6 by flg22, HrpZ or NPP1
Li,2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
Shan,2008
-
IDA
A thal
reduces upregulation of FRK1 by flg22, elf18, HrpZ, PGN, LPS, chitin, NPP!
negative regulation by symbiont of host defense-related protein level 
P
He, 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1 by flg22, HrpZ or NPP1
Li,2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
He, 2006
-
IDA
A thal Col-0
reduces upregulation of MPK3, MPK6 by flg22, HrpZ or NPP1
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Hann&Rathjen, 2007
-
IDA
N benth
reduces upregulation of ROS by PtabF
modulation by symbiont of ethylene levels in host
P
Cohn, 2005
-
IEP
S lyco Rio Grande
upregulates LeACO1 LeACO2
modulation by symbiont of host RNA levels
P
Navarro, 2008
-
IDA
A thal Col-0
reduces miR39, miR171, miR173 levels

 


avrPtoB (hopAB2)
host cell cytoplasm
C
deVries, 2006
-
IDA
N benth
-
protein kinase binding
F
Kim, 2002
-
IPI
S lyco Rio Grande
binds Pto
Rosebrock, 2007
-
IPI
S pimp
binds Pto
Rosebrock, 2007
-
IPI
S pimp
binds Fen
Shan,2008
-
IPI
A thal
binds BAK1
protein binding
F
Rosebrock, 2007
-
IPI
S pimp
binds PtoC
protein ubiquitination 
F
Rosebrock, 2007
-
IPI
S pimp
ubiquitinates Fen
ubiquitin-protein ligase activity
F
Janjusevic, 2006
-
IDA
-
-
ubiquitin conjugating enzyme binding
F
Janjusevic, 2006
-
IMP
-
-
Janjusevic, 2006
UniProt:
P62877,
Q8VZ40
ISS
-
-
pathogenesis
P
Abramovitch, 2003
-
IDA
S lyco Rio Grande
-
Jamir, 2004
-
IDA
N tab xanthi
-
Jamir, 2004
-
IDA
A thal Ws-0
-
interaction with host via protein secreted by type III secretion system
P
Kim,2002
-
IDA
S lyco Rio Grande
-
positive regulation of growth or development of symbiont during interaction with host 
P
He, 2006
-
IDA
A thal Col-0
-
Lin and Martin 2005
-
IDA
S lyco Rio Grande
-
negative regulation by symbiont of host molecular function
P
Rosebrock, 2007
-
IDA
S pimp
reduces Fen function
positive regulation by symbiont of host defense-related PCD
P
Kim,2002
-
IDA
S lyco Rio Grande
-
negative regulation by symbiont of host defense-related PCD
P
Jamir, 2004
-
IDA
N tab xanthi
-
Abramovitch, 2003
-
IDA
N benth
-
Jamir, 2004
-
IDA
A thal Ws-0
-
Janjusevic, 2006
-
IMP
S lyco
-
negative regulation by symbiont of host defense-related protein level 
P
Jamir, 2004
-
IDA
N tab xanthi
reduces upregulation of PR1a expression by HopA1
Rosebrock, 2007
-
IDA
S lyco Rio Grande
degrades Fen (S pimp)
He, 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1 by flg22, HrpZ or NPP1
negative regulation by symbiont of host resistance gene-dependent defense response
P
Abramovitch, 2003
-
IDA
N benth
reduces HR elicited by Avr9-Cf9 interaction
Abramovitch, 2003
-
IDA
S lyco Rio Grande
reduces HR elicited by AvrPto-Pto interaction
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
He, 2006
-
IDA
A thal Col-0
reduces upregulation of MPK3, MPK6 by flg22, HrpZ or NPP1
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Hann&Rathjen, 2007
-
IDA
N benth
reduces upregulation of ROS by PtabF
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
He, 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1, MPK3, MPK6 by flg22, HrpZ or NPP1
modulation by symbiont of ethylene levels in host
P
Cohn & Martin, 2005
-
IEP, IMP
S lyco Rio Grande
upregulates LeACO1LeACO2
negative regulation by symbiont of host apoptosis
P
Abramovitch, 2003
-
IDA
N benth
-
negative regulation by symbiont of host programmed cell death
P
Abramovitch, 2003
-
IDA
S cerevisiae
-
modulation by symbiont of host RNA levels
P
Navarro, 2008
-
IDA
A thal Col-0
reduces pri-miR393a and pri-miR393b levels

 


hopA1
host cell
C
Chang,2005
-
IDA
A thal Col-0
-
chaperone binding
F
Alfano,2000
hopA1 (Psy 61)
ISS
-
-
pathogenesis
P
Alfano,2000
hopA1 (Psy 61)
ISS
N tab xanthi
-
interaction with host via protein secreted by type III secretion system