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P. syringae - Plant Interaction Resource

genome resources
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Genomic analyses are revealing an increasingly complex web of interactions occurring between pathogen and host gene products. Systematic characterizations of these interactions is being modeled using Gene Ontology (GO) Annotation.

Virulence factors with associated GO annotation

View interaction diagram Download, sort, and print annotations in Excel

Key to modified Gene Ontology Annotation used to describe the Pto DC3000-host interaction
Frequently Asked Questions

Pto DC3000 Hop effector proteins
avrE1(10-08-13)
avrPto (10-08-13)
avrPtoB (hopAB2) (10-08-13)
hopA1 (06-18-12)
hopB1 (04-31-09)
hopC1 (06-15-09)
hopD1 (12-22-09)
hopE1 (10-08-13)
hopF2 (11-13-13)
hopG1 (12-22-09)
hopH1 (04-31-09)
hopI1(10-08-13)
hopK1 (12-18-13)
hopM1 (10-08-13)
hopN1 (2012)
hopO1-1(10-08-13)
hopO1-2 (04-31-09)
hopQ1-1 10-16-13)
hopQ1-2
hopR1(10-08-13)
hopS1 (04-31-09)
hopS2 (12-22-09)
hopT1-1 (04-31-09)
hopT1-2 (04-31-09)
hopU1 (02-13-12)
hopV1 (04-31-09)
hopX1 (04-18-14)
hopY1 (04-31-09)
hopAA1-1(10-08-13)
hopAA1-2 (04-31-09)
hopAF1 (04-31-09)
hopAH1 (04-31-09)
hopAH2-1 (04-31-09)
hopAH2-2 (04-31-09)
hopAI1 (04-31-09)
hopAM1-1 (12-22-09)
hopAM1-2 (12-22-09)
hopAO1 (04-18-14)
hopAQ1
 
Hop effector proteins (not present in Pto DC3000)
avrA1 (04-31-09)
avrB1 (02-19-10)
avrB2 (04-18-14)
avrRpm1 (10-08-13)
avrRps4 (12-18-13)
avrRpt2 (10-08-13)
hopF1 (10-08-13)
hopW1(10-08-13)
hopZ1a (11-13-13)
hopZ2 (10-08-13)
hopZ3 (10-08-13)
hopZ4 (04-18-14)
hopAS1 (10-08-13)
-
Harpins, pilus-associated proteins, and T3SS helpers
hrpA1 (04-31-09)
hrpH1 (10-08-13)
hrpK1 (10-08-13)
hrpW1 (06-15-09)
hrpZ1 (06-15-09)
hopP1 (10-08-13)
hopAJ1 (04-31-09)
hopAK1 (04-31-09)
Toxins and other virulence factors
coronatine (10-08-13)
AprA (04-29-14)
-
-
Pamps
flagellin
LPS
EF-Tu
-


AvrE1 (PSPTO_1377)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Badel 2006
-
IDA
N benth
-
pathogenesis
P
Debroy 2004
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
Badel 2006
-
IDA
S. lyco Money maker
positive regulation of lesion number
interaction with host via protein secreted by type III secretion system
P
Badel 2006
-
IDA
N benth
-
positive regulation of growth of symbiont involved in interaction with host 
P
Badel 2006
HopM1 Q887D0
IGI
S. lyco Money maker
-
Debroy 2004
-
IDA
A thal Col-0
-
killing by symbiont of host cells 
P
Badel 2006
-
IDA
N benth
-
Badel 2006
-
IDA
N tab xanthi
-
Badel 2006
-
IDA
S lyco Money maker
-
positive regulation by symbiont of host defense-related PCD
P
Alfano 2000
avrE (Pto PT23)
ISS
Glycine max
-
Wei 2007
-
IDA
N benth
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Debroy 2004
-
IDA
A thal Col-0
negative regulation of Pto DC3000 deltaCEL-induced callose deposition
negative regulation by symbiont of host salicylic acid-mediated defense response
P
Debroy 2004
-
IGI
A thal Col-0
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Debroy 2004
-
IDA
A thal Col-0
-


avrPto
(PSPTO_4001) (RefSeq link) (PDB structures: 1R5E, 2QKW)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell plasma membrane
C
Shan 2000
-
IDA
N tab W38
-
protein kinase binding
F
Scofield 1996
-
IPI
S lyco Rio Grande
binds Pto
Xiang 2008
-
IPI IMP
A thal Col-0
binds FLS2
Xiang 2008
-
IPI
A thal Col-0
binds EFR
Xiang 2008
-
IPI IMP
S lyco Money maker
binds LeFLS2
Shan 2008
-
IPI
A thal
binds BAK1
Xiang 2011
-
IPI
A thal
binds BSK3
Xiang 2011
-
IPI
A thal
binds CDG1
Xiang 2008
-
IPI
A thal
binds At2g23200
protein binding
F
Luo 2009
-
IPI
S lyco
binds RIN4
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
He 2006
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
Hauck 2003
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Schechter 2004 
-
IDA
S lyco Money maker
-
Schechter 2004 
-
IDA
N benth
-
positive regulation of growth of symbiont involved in interaction with host 
P
Chang 2000
-
IDA
S lyco Rio Grande 76
-
Hauck 2003
-
IDA
A thal Col-0
-
positive regulation by symbiont of host defense-related PCD
P
Ronald 1992
-
IDA
S lyco Rio Grande 76
positive regulation of Pto - dependent defense-related PCD
negative regulation by symbiont of defense-related host callose deposition
P
Hauck 2003
-
IDA
A thal Col-0
negative regulation of callose deposition induced by hrcC- DC3000
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Hauck 2003
-
IDA
A thal Col-0
negative regulation of callose deposition induced by hrcC- DC3000
He 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1, MPK3, MPK6 by flg22, HrpZ or NPP1
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
Shan 2008
-
IDA
A thal
reduces upregulation of FRK1 by flg22, elf18, HrpZ, PGN, LPS, chitin, NPP1
negative regulation by symbiont of host defense-related protein level 
P
He 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1 by flg22, HrpZ or NPP1
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
Luo 2009
S lyco Pto
IDA
N benth
degrades transgenic S lyco RIN4
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
He 2006
-
IDA
A thal Col-0
reduces upregulation of MPK3, MPK6 by flg22, HrpZ or NPP1
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Hann&Rathjen 2007
-
IDA
N benth
reduces upregulation of ROS by PtabF
positive regulation by symbiont of ethylene levels in host
P
Cohn 2005
-
IEP
S lyco Rio Grande
upregulates LeACO1 LeACO2
negative regulation by symbiont of RNA levels in host
P
Navarro 2008
-
IDA
A thal Col-0
reduces miR39, miR171, miR173 levels
positive regulation by symbiont of host resistance gene-dependent defense response
P
Ronald 1992
-
IDA
S lyco Rio Grande 76
positive regulation of Pto - dependent defense-related PCD

 


avrPtoB (hopAB2) (PSPTO_3087)
(RefSeq link)
(PDB structures: 3TL8, 3HGL, 2LF6, 3TJY, 2LF3, 3SVI)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell cytoplasm
C
deVries 2006
-
IDA
N benth
-
protein kinase binding
F
Kim 2002
-
IPI
S lyco Rio Grande
binds Pto
Rosebrock 2007
-
IPI
S pimp
binds Pto
Rosebrock 2007
-
IPI
S pimp
binds Fen
Shan 2008
-
IPI
A thal
binds BAK1
Gohre, 2008
-
IPI
A thal
binds FLS2
Gimenez-Ibanez, 2009
-
IPI
A thal
binds CERK1
Zeng 2012
-
IPI
S lyco
binds Bti9
Zeng 2012
-
IPI
S lyco
binds SlLyk13
protein binding
F
Rosebrock 2007
-
IPI
S pimp
binds PtoC
Luo 2009
-
IPI
S lyco
binds RIN4
Luo 2009
-
IPI
A thal
binds RIN4
modification by symbiont of host protein by ubiquitination  
P
Rosebrock 2007
-
IPI
S pimp
ubiquitinates Fen
Gohre, 2008
-
IDA
A thal
ubiquitinates FLS2
Gimenez-Ibanez, 2009
-
IDA
A thal
ubiquitinates CERK1
ubiquitin-protein ligase activity
F
Janjusevic 2006
-
IDA
-
-
ubiquitin conjugating enzyme binding
F
Janjusevic 2006
-
IMP
-
-
Janjusevic 2006
UniProt:
P62877 Q8VZ40
ISS
-
-
pathogenesis
P
Abramovitch 2003
-
IDA
N benth
negative regulation by symbiont of host resistance gene-dependent defense response
Jamir 2004
-
IDA
N tab xanthi
negative regulation by symbiont of host defense-related PCD
Jamir 2004
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
He 2006
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Kim 2002
-
IDA
S lyco Rio Grande
-
positive regulation of growth of symbiont involved in interaction with host 
P
He 2006
-
IDA
A thal Col-0
-
Lin and Martin 2005
-
IDA
S lyco Rio Grande
-
positive regulation by symbiont of host resistance gene-dependent defense response
P
Kim 2002
-
IDA
S lyco Rio Grande
positive regulation of Pto - dependent defense-related PCD
positive regulation by symbiont of host defense-related PCD
P
Kim 2002
-
IDA
S lyco Rio Grande
positive regulation of Pto - dependent defense-related PCD
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
N tab xanthi
-
Abramovitch 2003
-
IDA
N benth
reduces HR elicited by Avr9-Cf9 interaction and AvrPto-Pto interaction
Jamir 2004
-
IDA
A thal Ws-0
-
Janjusevic 2006
-
IMP
S lyco
-
negative regulation by symbiont of host defense-related protein level 
P
Jamir 2004
-
IDA
N tab xanthi
reduces upregulation of PR1a expression by HopA1
Rosebrock 2007
-
IDA
S lyco Rio Grande
degrades Fen (S pimp)
He 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1 by flg22 HrpZ or NPP1
Gohre, 2008
-
IDA
A thal
degrades FLS2
Gimenez-Ibanez, 2009
-
IDA
A thal
reduces upregulation of At1g51890 and At4g20780
Gimenez-Ibanez, 2009
-
IDA
A thal
degrades CERK1
Ntoukakis,2009
-
IDA
S lyco Rio Grande
reduced levels of Prf
Luo 2009
S lyco Pto
IDA
N benth
degrades transgenic S lyco RIN4
negative regulation by symbiont of host resistance gene-dependent defense response
P
Abramovitch 2003
-
IDA
N benth
reduces HR elicited by Avr9-Cf9 interaction
Abramovitch 2003
-
IDA
N benth
reduces HR elicited by AvrPto-Pto interaction
negative regulation by symbiont of host resistance gene-dependent defense response
P
Guo 2009
  19656042 
-
IDA
A thal Col-0
reduces HR elicited by AvrRpm1-RPM1 interaction
Guo 2009
  19656042 
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
He 2006
-
IDA
A thal Col-0
reduces upregulation of MPK3 MPK6 by flg22 HrpZ or NPP1
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Hann&Rathjen 2007
-
IDA
N benth
reduces upregulation of ROS by PtabF
Gimenez-Ibanez, 2009
-
IDA
A thal
reduces upregulation of ROS induced by chitin
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
He 2006
-
IDA
A thal Col-0
reduces upregulation of FRK1, MPK3, MPK6 by flg22, HrpZ or NPP1
de Torres 2006
-
IDA
A thal Nd-1
reduces callose deposition induced by flg22
positive regulation by symbiont of ethylene levels in host
GO:1990212
P
Cohn & Martin 2005
-
IEP, IMP
S lyco Rio Grande
upregulates LeACO1LeACO2
negative regulation by symbiont of host apoptosis
P
Abramovitch 2003
-
IDA
N benth
-
negative regulation by symbiont of host programmed cell death
P
Abramovitch 2003
-
IDA
S cerevisiae
-
negative regulation by symbiont of RNA levels in host
P
Navarro 2008
-
IDA
A thal Col-0
reduces pri-miR393a and pri-miR393b levels
negative regulation by symbiont of defense-related host callose deposition
P
de Torres 2006
-
IDA
A thal Nd-1
negative regulation of callose deposition induced by flg22
Gimenez-Ibanez, 2009
-
IDA
A thal
negative regulation of callose deposition induced by chitin
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by AvrRpm1
positive regulation by symbiont of abscisic acid levels in host
GO:1990218
P
de Torres-Zabala 2007
-
IEP
A thal
ABA biosynthetic enzyme NCED3 transcripts positively regulated

 


hopA1 (PSPTO_5354)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell plasma membrane
C
Salomon 2013
-
IDA
S lyco
-
chaperone binding
F
Alfano 2000
hopA1 (Psy 61)
ISS
-
-
interaction with host via protein secreted by type III secretion system 
P
Chang 2005
-
IDA
A thal Col-0
-
phosphatidylinositol binding
C
Salomon 2013
-
IDA
-
-
positive regulation by symbiont of host defense-related PCD
P
Alfano 2000
hopA1 (Psy 61)
ISS
N tab xanthi
-
Alfano 2000
hopA1 (Psy 61)
ISS
A thal Col-0
-
positive regulation by symbiont of host resistance gene-dependent defense response
P
Kim 2009
-
IMP
A thal Col-0
RPS6-dependent defense-related PCD
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Oh 2010
-
IDA
N benth
reduces bacterially induced ROS production
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Oh 2010
-
IDA
N benth
reduces bacterially induced ROS production
positive regulation by symbiont of host defense-related protein level
P
Nomura 2011
-
IDA
A thal Col-0
HopA1-induced ETI lessened AtMIN7 degradation caused by HopM1
protein binding
F
Bhattacharjee 2012
-
IPI
N benth
binds EDS1



hopB1 (PSPTO_1406)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Petnicki 2005
-
IDA
A thal Col-0
-
Petnicki 2005
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system 
P
Petnicki 2005
-
IDA
A thal Col-0
-
Petnicki 2005
-
IDA
N benth
-

 


hopC1 (PSPTO_0589)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Schechter 2004 
-
IDA
N benth
-
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Schechter 2004 
-
IDA
N benth
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
cysteine-type peptidase activity 
F
Shao 2002
-
IMP
-
-
Shao 2002
YopT (Y. pestis)
ISS
-
-

 


hopD1 (PSPTO_0876)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Chang 2005
hopD1 (Pph 1448A)
ISS
A thal Col-0
-
pathogenesis
P
Jamir 2004
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
Jamir 2004
-
IDA
N tab xanthi
negative regulation by symbiont of host defense-related PCD
positive regulation of growth of symbiont involved in interaction with host
P
Block 2013
-
IDA
A thal Col-0
-
transcription factor binding transcription factor activity
F
Mukhtar 2011
-
IPI
A thal
binds transcription factor NTL9
transcription factor binding transcription factor activity
F
Block 2013
-
IPI
A thal Col-0
binds transcription factor NTL9
interaction with host via protein secreted by type III secretion system
P
Chang 2005
hopD1 (Pph 1448A)
ISS
A thal Col-0
-
positive regulation by symbiont of host defense-related PCD
P
Arnold 2001
hopD1 (Pph 1302A)
ISS
P sativum
-
modification by symbiont of host morphology or physiology
P
Munkvold 2008
-
IDA
S cerevisiae
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
negative regulation by symbiont of host resistance gene-dependent defense response
P
Block 2013
-
IDA
A thal Col-0
reduces HR elicited by AvrRpm1- RPM1 interaction
negative regulation by symbiont of host defense-related protein level 
P
Block 2013
-
IDA
A thal Col-0
reduction in FRK1, PAL1, NHL10 levels
negative regulation by symbiont of host protein levels
P
Block 2013
-
IDA
A thal Col-0
reduction in ADF6, HAB1, NIP2 levels
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
N tab xanthi
-
Jamir 2004
-
IDA
A thal Ws-0
-

 


hopE1
(PSPTO_4331) (RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Zwiesler-Vollick 2002
-
IDA
A thal Col-0
-
pathogenesis
P
Jamir 2004
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
Jamir 2004
-
IDA
N tab xanthi
negative regulation by symbiont of host defense-related PCD
Guo 2009
-
IDA
A thal
negative regulation of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system 
P
Zwiesler-Vollick 2002
-
IDA
A thal Col-0
-
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
N tab xanthi
-
Jamir 2004
-
IDA
A thal Ws-0
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Guo 2009
-
IDA
A thal
negative regulation of callose deposition induced by Pseudomonas fluorescens
negative regulation by symbiont of host defense-related protein level 
P
Jamir 2004
-
IDA
N tab xanthi
reduces upregulation of PR1a expression by HopA1
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by AvrRpm1
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by Pseudomonas fluorescens
positive regulation of growth of symbiont involved in interaction with host
P
Cunnac 2011
-
IDA
N benth
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Guo 2009
  19656042 
-
IDA
A thal Col-0
reduces HR elicited by AvrRpm1-RPM1 interaction
negative regulation by symbiont of host apoptosis
P
Jamir 2004
-
IDA
S cerevisiae
-
Jamir 2004
-
IDA
N benth
-

 


hopF2 (PSPTO_0502)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell plasma membrane 
C
Robert-Seilaniantz 2006
-
IDA
N tab xanthi
-
Robert-Seilaniantz 2006
-
IDA
A thal
-
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
F
Wang 2010
IDA
A thal
ADP-ribosylation of MKK5 and RIN4
chaperone binding
F
Shan 2004

ShcF2
(Q7WYY9)

IPI
-
-
Shan 2004

ShcF2
(Q7WYY9)

IGC
-
-
protein binding
F
Wilton 2010
-
IDA
A thal Col-0
binds RIN4
protein kinase binding
F
Zhou 2013
IPI
A thal
binds BAK1
protein kinase binding
F
Wang 2010
IPI
A thal
binds MKK3, MKK4, MKK5, MKK6, MKK10
pathogenesis
P
Robert-Seilaniantz 2006
-
IDA
S lyco Rio grande
positive regulation of lesion number
Jamir 2004
-
IDA
N tab xanthi
negative regulation by symbiont of host defense-related PCD
Jamir 2004
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
Li 2005
-
IDA
A thal Col-0
negative regulation of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Shan 2004
ShcF2
(Q7WYY9)
IGI
A thal Col-0
-
positive regulation of growth of symbiont involved in interaction with host 
P
Robert-Seilaniantz 2006
-
IDA
S lyco Rio grande
-
Guo 2009
-
IDA
A thal
-
Wilton 2010
-
IDA
A thal Col-0
positive regulation dependent upon presence of RIN4
killing by symbiont of host cells 
P
Robert-Seilaniantz 2006
-
IDA
S lyco Rio grande
-
positive regulation by symbiont of host defense-related PCD
P
Robert-Seilaniantz 2006

-

IDA
N tab W38
-
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
N tab xanthi
-
Jamir 2004
-
IDA
A thal Ws-0
-
Wilton 2010
-
IDA
A thal Col-0
-
negative regulation by symbiont of host defense-related protein level 
P
Jamir 2004
-
IDA
N tab xanthi
reduces upregulation of PR1a expression by HopA1
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
modification by symbiont of host protein
P
Wang 2010
IDA
A thal
ADP-ribosylation of MKK5 and RIN4
negative regulation by symbiont of host resistance gene-dependent defense response
P
Guo 2009
  19656042 
-
IDA
A thal Col-0
reduces HR elicited by AvrRpm1-RPM1 interaction
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
Wilton 2010
-
IDA
A thal Col-0
reduces HR elicited by AvrRpt2-RPS2 interaction
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
Wang 2010
-
IDA
A thal
negative regulation of PAMP-triggered phosphorylation of MPK3 and MPK6
Wu 2011
-
IDA
A thal Col-0
reduces upregulation of FRK1, MPK3, MPK6, MPK4 by flg22
Wu 2011
-
IDA
A thal Col-0
reduces upregulation of FRK1, MPK3, MPK6 by elf18
Wu 2011
-
IDA
A thal Col-0
reduces upregulation of FRK1 by peptidoglycan, LPS, HrpZ, chitin
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by AvrRpm1
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by Pseudomonas fluorescens
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
GO:0052078
P
Wang 2010
-
IDA
A thal
negative regulation of PAMP-triggered phosphorylation of MPK3 and MPK6
Wu 2011
-
IDA
A thal Col-0
reduces upregulation of MPK3, MPK6, MPK4 by flg22
Wu 2011
-
IDA
A thal Col-0
reduces upregulation of MPK3, MPK6 by elf18
negative regulation by symbiont of host apoptosis
P
Jamir 2004
-
IDA
S cerevisiae
-
Jamir 2004
-
IDA
N benth
-

 


hopG1 (PSPTO_4727)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell mitochondrion
C
Block 2009
-
IDA
N tab Xanthi
-
pathogenesis
P
Jamir 2004
-
IDA
N benth
negative regulation by symbiont of host defense-related PCD
interaction with host via protein secreted by type III secretion system 
P
Petnicki 2002
-
IDA
A thal Col-0
-
Block 2009
-
IDA
A thal Col-0
-
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
N tab Xanthi
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
negative regulation by symbiont of host apoptosis
P
Jamir 2004
-
IDA
S cerevisiae
-
Jamir 2004
-
IDA
N benth
-

 


hopH1 (PSPTO_0588)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Chang 2005
-
IDA
A thal Col-0
-
interaction with host via protein secreted by type III secretion system
P
Chang 2005
-
IDA
A thal Col-0
-


hopI1 (PSPTO_4776)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell chloroplast
C
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal Col
-
Jelenska 2007
hopI1 (Pma ES4326)
ISS
N tab Burley
-
Jelenska 2007
hopI1 (Pma ES4326)
ISS
N benth
-

protein binding

F
Jelenska 2010
hopI1 (Pma ES4326)
ISS
A thal
Hsp70
interaction with host via protein secreted by type III secretion system 
P
Chang 2005
-
IDA
A thal Col-0
-
pathogenesis
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal
negative regulation by symbiont of host SA-mediated defense response
Jelenska 2010
hopI1 (Pma ES4326)
ISS
S lyco cv Bonnie Best
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326)
ISS
P sativum 
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326)
ISS
R sativus
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326)
ISS
B oleracea Acephala Group
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326)
ISS
B oleracea Botrytis Group
positive regulation of lesion number 
positive regulation of growth of symbiont involved in interaction with host  
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
N tab Burley
-
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal
-
Jelenska 2007
hopI1 (Pma ES4326)
ISS
N. benth
-
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
S lyco cv Bonnie Best
-
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
P sativum 
-
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
R sativus
-
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
B oleracea Acephala Group
-
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
B oleracea Botrytis Group
-
killing by symbiont of host cells 
P
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
S lyco cv Bonnie Best
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
P sativum 
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
R sativus
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
B oleracea Acephala Group
positive regulation of lesion number 
Jelenska 2010
hopI1 (Pma ES4326) 
ISS
B oleracea Botrytis Group
positive regulation of lesion number 
modification by symbiont of host chloroplast thylakoid 
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal
-
Jelenska 2007
hopI1 (Pma ES4326)
ISS
N benth
-
negative regulation by symbiont of host salicylic acid-mediated defense response
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal
decreased free and total SA levels in acd6-1 plants
negative regulation by symbiont of host defense-related protein level 
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal
reduces PR1 expression in acd6-1 plants
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Jelenska 2010
hopI1 (Pma ES4326)
ISS
N benth
HopI1 or hrp70-increased growth of hrcC- P. syringae
positive regulation by symbiont of host adenylate cyclase activity
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
S cerevisiae ACY95b
stimulates Hsp70 ATPase activity
modulation by symbiont of host response to heat
P
Jelenska 2007
hopI1 (Pma ES4326)
ISS
A thal
-



hopK1 (PSPTO_0044)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell chloroplast
C
Li 2013
-
IDA
N benth
-
host cell chloroplast
C
Li 2013
-
IDA
A thal
-
interaction with host via protein secreted by type III secretion system
P
Petnicki 2002
-
IDA
A thal Col-0
-
Schechter 2004
-
IDA
N benth
-
positive regulation by symbiont of host defense-related PCD
P
Schechter 2004
-
IDA
N benth
-
positive regulation by symbiont of host defense-related protein level
P
He 2004
-
IMP
A thal Col-0
reduced upregulation of RAP2.6 in hopK1 mutant
negative regulation by symbiont of host defense-related PCD
P
Guo 2009
-
IDA
N tab xanthi
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Guo 2009
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
pathogenesis
P
Guo 2009
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
pathogenesis
P
Li 2013
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
pathogenesis
P
Li 2013
-
IDA
A thal Col-0
positive regulation of lesion number
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2013
-
IDA
A thal Col-0
negative regulation of flg22, elf, or chitin induced callose deposition or ROS
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Li 2013
-
IDA
A thal Col-0
negative regulation of flg22, elf, or chitin induced callose deposition
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Li 2013
-
IDA
A thal Col-0
negative regulation of flg22, elf, or chitin induced ROS
positive regulation of growth of symbiont involved in interaction with host
P
Li 2013
-
IDA
A thal Col-0
-



hopM1 (PSPTO_1375)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell endomembrane system
C
Nomura 2006
-
IDA
A thal
-
small GTPase binding  (covers ARF and GEF)
F
Nomura 2006
-
IPI
A thal Col-0
binds AtMIN7
protein binding
F
Nomura 2006
-
IPI
S cerevisiae
chaperone binding
P
Badel 2003
ShcM (Q9JP35)
IPI
-
-
pathogenesis
P
Debroy 2004
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
Badel 2006
AvrE (Q7BM43)
IGI
 S lyco Money maker
positive regulation of lesion number
interaction with host via protein secreted by type III secretion system 
P
Badel 2003
ShcM (Q9JP35)
IGI
A thal Col-0
-
positive regulation of growth of symbiont involved in interaction with host   
P
Nomura 2006
-
IDA
A thal Col-0
-
Badel 2006
AvrE (Q7BM43)
IGI
S lyco Money maker
-
killing by symbiont of host cells 
P
Badel 2003
-
IMP
S lyco Money maker
-
Debroy 2004
-
IDA
A thal Col-0
-
negative regulation by symbiont of host protein levels
GO:1990214 
P
Nomura 2006
-
IDA
S cerevisiae
destabilizes AtMIN7AtMIN2 AtMIN10
Nomura 2006
-
IDA
N benth
destabilizes AtMIN7AtMIN2 AtMIN10
Nomura 2006
-
IDA
A thal Col-0
destabilizes AtMIN7 AtMIN10
positive regulation by symbiont of host defense-related PCD
P
Badel 2006
AvrE (Q7BM43)
IGI
N benth
-
Wei 2007
-
IDA
N benth
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Debroy 2004
-
IDA
A thal Col-0
negative regulation of Pto DC3000 deltaCEL-induced callose deposition
negative regulation by symbiont of host salicylic acid-mediated defense response
P
Debroy 2004
AvrE (Q7BM43)
IGI
A thal Col-0
restores growth of HopM1/ AvrE1 mutant in Eds5 host
negative regulation by symbiont of host defense-related protein level 
P
Ham 2007
-
IDA
A thal Col-0
reduced upregulation of PR-1 by wt Pph
negative regulation by symbiont of host defense-related protein level 
P
Gangadharan 2013
-
IDA
A thal Col-0
reduced upregulation of PR-1 by wt Pph, SQ-independent
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Debroy 2004
-
IDA
A thal Col-0
-
modification by symbiont of host protein by ubiquitination
P
Nomura 2006
-
IDA
N benth
AtMIN7 ubiquitination mediated by HopM1
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Lozano-Duran 2013
-
IDA
A thal Col-0
negative regulation of flg22 or chitin induced ROS
regulation of stomatal closure
P
Lozano-Duran 2013
-
IDA
A thal Col-0
negative regulation of flg22 or chitin induced stomatal closure



hopN1 (PSPTO_1370)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell chloroplast thylakoid membrane
C
Rodriguez-Herva 2012
-
IDA
N benth
-
cysteine-type peptidase activity 
F
Lopez-Solanilla 2004
-
IDA
-
-
protein binding
F
Rodriguez-Herva 2012
-
IPI
S lyco Money maker
binds PsbQ
chaperone binding
F
Lopez-Solanilla 2004
ShcN
IGI
-
-
Lopez-Solanilla 2004
ShcN
IGC
-
-
pathogenesis
P
Lopez-Solanilla 2004
-
IDA
N benth
negative regulation by symbiont of host defense-related PCD-
Lopez-Solanilla 2004
-
IDA
N tab Xanthi
negative regulation by symbiont of host defense-related PCD
Rodriguez-Herva 2012
-
IDA
A thal
negative regulation by symbiont of PAMP-induced host innate immunity
Rodriguez-Herva 2012
-
IDA
S lyco Money maker
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Lopez-Solanilla 2004
-
IDA
S lyco Money maker
-
negative regulation by symbiont of RNA levels in host
P
Navarro 2008
-
IDA
A thal Col-0
reduces miR39 and tas255 levels
modification by symbiont of host morphology or physiology
P
Munkvold 2008
-
IDA
S cerevisiae
-
negative regulation by symbiont of host protein levels
GO:1990214  
P
Rodriguez-Herva 2012
-
IDA
S lyco Money maker
reduction in PsbQ levels
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Rodriguez-Herva 2012
-
IDA
A thal Col-0
-
Rodriguez-Herva 2012
-
IDA
S lyco Money maker
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Rodriguez-Herva 2012
-
IDA
A thal Col-0
-
Rodriguez-Herva 2012
-
IDA
S lyco Money maker
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Rodriguez-Herva 2012
-
IDA
A thal Col-0
reduces P. fluorescens induced callose production
Rodriguez-Herva 2012
-
IDA
S lyco Money maker
reduces P. fluorescens induced callose production
negative regulation by symbiont of host defense-related PCD
P
Lopez-Solanilla 2004
-
IDA
N benth
-
Lopez-Solanilla 2004
-
IDA
N tab Xanthi
-

 


hopO1-1 (PSPTO_A0018)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Guo 2005
-
IDA
N benth
-
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
F
Fu 2007
HopU1 (Pto DC3000)
ISS
-
-
chaperone binding
F
Guo 2005
ShcO1
(Q88BP9)
IPI
-
-
Guo 2005
ShcS1
(Q87WF2)
IPI
-
-
Guo 2005
ShcS2 (Q87WG1)
IPI
-
-
interaction with host via protein secreted by type III secretion system 
P
Guo 2005
ShcO1
(Q88BP9)
IGI
N benth
-
Guo 2005
ShcS1
(Q87WF2)
IGI
N benth
-
Guo 2005
ShcS2 (Q87WG1)
IGI
N benth
-
positive regulation of growth of symbiont involved in interaction with host
P
Guo 2005
-
IDA
A thal Col-0
-


hopO1-2 (PSPTO_4594)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Chang 2005
-
IDA
A thal Col-0
-
protein binding
F
Guo 2005
ShcO1
(Q88BP9)
IPI
-
-
Guo 2005
ShcS1
(Q87WF2)
IPI
-
-
Guo 2005
ShcS2 (Q87WG1)
IPI
-
-
interaction with host via protein secreted by type III secretion system 
P
Chang 2005
-
IDA
A thal Col-0
-
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
F
Fu 2007
HopU1 (Pto DC3000)
ISS
-
-


hopQ1-1 (PSPTO_0877)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell cytoplasm
C
Giska 2013
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system
P
Schechter 2004
-
IDA
N benth
-
killing by symbiont of host cells 
P
Robert-Seilaniantz 2006
-
IDA
N tab W38
-
positive regulation by symbiont of host defense-related PCD
P
Schechter 2004
-
IDA
N benth
-
pathogenesis
P
Ferrante 2009
hopQ1-1 (Pph 1448A)
ISS
P vulgaris
positive regulation of lesion size
pathogenesis
P
Hann 2013
-
IDA
A thal
negative regulation of PAMP-induced host innate immunity
positive regulation of growth of symbiont involved in interaction with host
P
Ferrante 2009
hopQ1-1 (Pph 1448A)
ISS
P vulgaris
-
positive regulation of growth of symbiont involved in interaction with host
P
Li 2013a
-
IDA
A thal
dependent on hydrolase domain
protein binding
F
Giska 2013
-
IPI
N benth
binds 14-3-3a
Giska 2013
-
IPI
P vulgaris
binds 14-3-3a
Li 2013b
-
IDA
S lyco
binds 14-3-3a proteins TFT1,5,4,9,3,6,10,2,7
hydrolase activity
P
Li 2013a
PDB: 1Q8F
ISS
-
-
hydrolase activity
P
Hann 2013
-
IDA
A thal
hydrolysis of iPRMP
modulation by symbiont of host cellular process
P
Li 2013a
-
IDA
A thal
altered levels of cellular nucleosides
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Hann 2013
-
IDA
A thal
reduces flg22 induced ROS production
negative regulation by symbiont of RNA levels in host
P
Hann 2013
-
IDA
A thal
reduces FLS2 mRNA levels
positive regulation by symbiont of RNA levels in host
P
Hann 2013
-
IDA
A thal
positive regulation of ARR5, ARR6, ARR2 mRNAs
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
Hann 2013
-
IDA
A thal
reduces upregulation of MPK3 and MPK6,by flg22
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Hann 2013
-
IDA
A thal
reduces flg22 induced ROS production
positive regulation by symbiont of cytokinin levels in host
GO:1990223
P
Hann 2013
-
IDA
A thal
-

 


hopR1 (PSPTO_0883)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
  Schechter 2006
  17073301 
-
IDA
N benth
-
Chang 2005
-
IDA
A thal Col-0
-
positive regulation of growth of symbiont involved in interaction with host
P
Kvitko 2009
-
IDA
N benth
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
  Kvitko 2009
  19381254 
-
IDA
N benth
negative regulation of bacterially-induced callose deposition
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
  Kvitko 2009
-
IDA
N benth
negative regulation of bacterially-induced callose deposition
pathogenesis
P
  Kvitko 2009
-
IDA
N benth
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system 
P
Schechter 2006
-
IDA
N benth
-
Chang 2005
-
IDA
A thal Col-0
-

 


hopS1 (PSPTO_4597)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Schechter 2004 
-
IDA
N benth
-
Kabisch 2005
-
IDA
A thal Col-0
-
interaction with host via protein secreted by type III secretion system
P
Schechter 2004 
ShcS1
IGI
N benth
-
Kabisch 2005
ShcS1
IGI
A thal Col-0
-
Kabisch 2005
ShcO1
IGI
A thal Col-0
-
chaperone binding
F
Kabisch 2005
ShcS1
IPI
-
-
Kabisch 2005
ShcO1
IPI
-
-
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin

 


hopS2 (PSPTO_0883)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
 
Guo 2005
  15937188 
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system 
P
Guo 2005
  15937188 
ShcS2
IGI
N benth
-
negative regulation by symbiont of host defense-related PCD
P
Guo 2009
  19656042 
ShcS2
IDA
N tab Xanthi
-
pathogenesis
P
Guo 2009
  19656042 
ShcS2
IDA
N tab Xanthi
negative regulation by symbiont of host defense-related PCD
negative regulation by symbiont of host resistance gene-dependent defense response
P
Guo 2009
  19656042 
ShcS2
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
chaperone binding
F
Guo 2005
  15937188 
ShcS2
IDA
-
-
protein binding
F
Guo 2005
  15937188 
ShcS1
IDA
-
-
Guo 2005
  15937188 
ShcO1
IDA
-
-

 


hopT1-1 (PSPTO_A0019)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Schechter 2004 
-
IDA
N benth
-
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Schechter 2004 
-
IDA
N benth
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
positive regulation by symbiont of host defense-related PCD
P
Wei 2007
-
IDA
N benth
-
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin



hopT1-2 (PSPTO_4593)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Vinatzer 2005 
-
IDA
N benth
-
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Vinatzer 2005 
-
IDA
N benth
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin



hopU1 (PSPTO_0501)
(RefSeq link)
(PDB structures: 3UOJ)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell cytoplasm
C
Fu 2007
-
IDA
A thal Col-0
-
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
F
Fu 2007
-
IDA
-
-
Fu 2007
-
IDA
A thal Col-0

ADP-ribosylates cp29-RPB, cp31-RPB, RPB31, GRP7, GRP8

Fu 2007
-
IDA
N tab Xanthi
-
modification by symbiont of host protein
P
Fu 2007
-
IDA
A thal Col-0
pathogenesis
P
Fu 2007
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
Fu 2007
-
IDA
N tab Xanthi
negative regulation by symbiont of host defense-related PCD
positive regulation of growth of symbiont involved in interaction with host
P
Fu 2007
-
IMP
A thal Col-0
-
interaction with host via protein secreted by type III secretion system 
P
Fu 2007
-
IDA
N benth
-
negative regulation by symbiont of host defense-related PCD
P
Fu 2007
-
IDA
N tab Xanthi
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Fu 2007
-
IDA
A thal Col-0
negative regulation of callose deposition induced by flg22
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Fu 2007
-
IDA
A thal Col-0
reduces flg22- induced callose production
negative regulation by symbiont of host resistance gene-dependent defense response 
P
Fu 2007
-
IDA
A thal Col-0
reduces HR elicited by AvrRpt2-RPS2 interaction
modification by symbiont of host morphology or physiology
P
Munkvold 2008
-
IDA
S cerevisiae
-
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Nicaise 2013
-
IDA
A thal
reduces upregulation of ROS by flg22 or elf18
negative regulation by symbiont of host defense-related protein level 
P
Nicaise 2013
-
IDA
A thal
reduces upregulation of FLS2 by hrcC- DC3000
negative regulation by symbiont of host molecular function 
P
Nicaise 2013
-
IDA
A thal
reduces GRP7 binding of FLS2 mRNA
Nicaise 2013
-
IDA
A thal
reduces GRP7 binding of EFR mRNA

 


hopV1 (PSPTO_4720)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
 Schechter 2004
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system 
P
Schechter 2004
ShcV ( Q87W45)
IGI
N benth
-
Wehling 2004
ShcV ( Q87W45)
IGI
A thal Col-0
-
chaperone binding
P
Wehling 2004
ShcV ( Q87W45)
IPI
-
-
positive regulation by symbiont of host defense-related PCD
P
Wei 2007
-
IDA
N benth
-

 


hopX1 (PSPTO_A0012)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell cytoplasm
C
Nimchuk 2007
-
IDA
A thal Ws-0
-
interaction with host via protein secreted by type III secretion system
P
Schechter 2004 
-
IDA
N benth
-
cysteine-type peptidase activity 
F
Nimchuk 2007
-
IMP
-
-
positive regulation by symbiont of host resistance gene-dependent defense response
P
Nimchuk 2007
-
IDA
P vulgaris
positive regulation of R2-dependent defense-related PCD
pathogenesis
P
Guo 2009
-
IDA
A thal
negative regulation by symbiont of PAMP-induced host innate immunity
Jamir 2004
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
Jamir 2004
-
IDA
N tab Xanthi
negative regulation by symbiont of host defense-related PCD
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
N tab Xanthi
-
Jamir 2004
-
IDA
A thal Ws-0
-
negative regulation by symbiont of host defense-related protein level 
P
Jamir 2004
-
IDA
N tab Xanthi
reduces upregulation of PR1a expression by HopA1
positive regulation by symbiont of host defense-related protein level
P
He 2004
-
IMP
A thal Col-0
reduced upregulation of RAP2.6 in hopX1 mutant
negative regulation by symbiont of host protein levels
P
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
N benth
degradation of A thal JAZ1,2,4,5,7,9,11,12
protein binding
F
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
-
binding of A thal JAZ1,2,3,4,5,6,7,8,9,10
positive regulation by symbiont of host jasmonic acid-mediated defense response
P
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
A thal
positive regulation of JAZ5, 10, 12 transcript levels
positive regulation by symbiont of host jasmonic acid-mediated defense response
P
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
N benth
positive regulation of JA-dependent chlorosis
positive regulation of growth of symbiont involved in interaction with host 
P
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
A thal
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Guo 2009
  19656042 
-
IDA
A thal Col-0
reduces HR elicited by AvrRpm1-RPM1 interaction
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by AvrRpm1
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by Pseudomonas fluorescens
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Guo 2009
-
IDA
A thal
negative regulation of callose deposition induced by Pseudomonas fluorescens
positive regulation by symbiont of entry into host
P
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
A thal
opening of stomata
regulation of stomatal closure
P
Gimenez-Ibanez 2014
hopX1(Pta 11528)
ISS
A thal
opening of stomata
positive regulation by symbiont of host defense-related PCD
P
Nimchuk 2007
-
IDA
A thal Col-0
-
Nimchuk 2007
-
IDA
P vulgaris
R2-dependent defense-related PCD
Wei 2007
-
IDA
N benth
-
negative regulation by symbiont of host apoptosis
P
Jamir 2004
-
IDA
S cerevisiae
-
Jamir 2004
-
IDA
N benth
-

 


hopY1 (PSPTO_0061)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Vinatzer 2005
-
IDA
A thal Col-0
-
Schechter 2006
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system 
P
Vinatzer 2005
-
IDA
A thal Col-0
-
Schechter 2006
-
IDA
N benth
-

 


hopAA1-1 (PSPTO_1372)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Lindeberg 2005
HopAA1(Psy B728a)
ISS
A thal Col-0
-
host cell mitochondrion
C
Munkvold 2008
-
IDA
S cerevisiae
-
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Lindeberg 2005
HopAA1(Psy B728a)
ISS
A thal Col-0
-
positive regulation of growth of symbiont involved in interaction with host
P
Badel 2002
HopAA1-2
IGI
A thal
-
positive regulation by symbiont of host defense-related PCD 
P
Wei 2007
-
IDA
N benth
-
killing by symbiont of host cells 
P
Munkvold 2008
-
IDA
S cerevisiae
-
Munkvold 2008
-
IDA
S lyco Moneymaker
-
Munkvold 2008
-
IDA
N tab Xanthi
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin

 


hopAA1-2 (PSPTO_4718)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Lindeberg 2005
HopAA1(Psy B728a)
ISS
A thal
-
positive regulation of growth of symbiont involved in interaction with host
P
Badel 2002
HopAA1-1
IGI
A thal
-
interaction with host via protein secreted by type III secretion system
P
Lindeberg 2005
HopAA1(Psy B728a)
ISS
A thal
-

 


hopAF1 (PSPTO_1568)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Chang 2005
-
IDA
A thal Col-0
-
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Chang 2005
-
IDA
A thal Col-0
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin

 


hopAH1 (PSPTO_0905)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Vinatzer 2005 
-
IDA
A thal Col-0
-
interaction with host via protein secreted by type III secretion system 
P
Vinatzer 2005 
-
IDA
A thal Col-0
-

 


hopAH2-1 (PSPTO_3292)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Vinatzer 2005 
-
IDA
A thal Col-0
-
Schechter 2006
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system 
P
Vinatzer 2005 
-
IDA
A thal Col-0
-
Schechter 2006
-
IDA
N benth
-


hopAH2-2 (PSPTO_3293)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Schechter 2006
-
IDA
N benth
-
interaction with host via protein secreted by type III secretion system 
P
Schechter 2006
-
IDA
N benth
-

 


hopAI1 (PSPTO_0906)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Vinatzer 2005 
-
IDA
A thal Col-0
-
phosphothreonine lyase activity
F
Zhang 2007
-
IDA
-
reduces phosphorylation of MPK3 MPK6
protein kinase binding
F
Zhang 2007
-
IPI
A thal Col-0
binds MPK3 MPK6
pathogenesis
P
Li 2005
-
IDA
A thal Col-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system
P
Vinatzer 2005 
-
IDA
A thal Col-0
-
positive regulation of growth of symbiont involved in interaction with host
P
Li 2005
-
IDA
A thal Col-0
-
Zhang 2007
-
IDA
S lyco Rio Grande
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
Zhang 2007
-
IDA
A thal Col-0
-
negative regulation by symbiont of host defense-related protein level 
P
Li 2005
-
IDA
A thal Col-0
reduces upregulation of NHO1 by flagellin
negative regulation by symbiont of host defense-related protein level 
P
Zhang 2007
-
IDA
A thal Col-0
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Zhang 2007
-
IDA
A thal Col-0
negative regulation of callose deposition induced by flg22
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Zhang 2007
-
IDA
A thal Col-0
-
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
Zhang 2007
-
IDA
A thal Col-0
reduces upregulation of MPK3 MPK6 by flagellin

 


hopAM1-1 (PSPTO_1022)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Chang 2005
-
IDA
A thal Col-0
-
pathogenesis
P
Jamir 2004
-
IDA
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
Jamir 2004
-
IDA
N tab Xanthi
negative regulation by symbiont of host defense-related PCD
Goel 2008
-
IDA
A thal Ws-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system 
P
Chang 2005
-
IDA
A thal Col-0
-
positive regulation of growth of symbiont involved in interaction with host
P
Goel 2008
-
IDA
A thal Ws-0
confers increased growth on Pma M6CΔE
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
-
IDA
A thal Ws-0
-
Jamir 2004
-
IDA
N tab Xanthi
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
killing by symbiont of host cells 
P
Munkvold 2008
-
IDA
S cerevisiae
-
negative regulation by symbiont of host apoptosis
P
Jamir 2004
-
IDA
S cerevisiae
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Goel 2008
-
IDA
A thal Ws-0
negative regulation of callose deposition induced by hrcC- DC3000
Guo 2009
  19656042 
-
IDA
A thal
negative regulation of callose deposition induced by AvrRpm1
modulation by symbiont of host signal transduction pathway
P
Goel 2008
-
IDA
A thal Ws-0
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Goel 2008
-
IDA
A thal Ws-0
reduces callose deposition induced by hrcC- DC3000
Guo 2009
  19656042 
-
IDA
A thal Col-0
reduces HR elicited by AvrRpm1-RPM1 interaction
positive regulation by symbiont of abscisic acid levels in host
GO:1990218
P
Goel 2008
-
IEP
A thal
ABA biosynthetic enzyme NCED3 transcripts positively regulated

 


hopAM1-2 (PSPTO_A0005)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell
C
Chang 2005
HopAM1-1 (Pto DC3000)
ISS
A thal Col-0
-
pathogenesis
P
Jamir 2004
HopAM1-1 (Pto DC3000)
ISS
A thal Ws-0
negative regulation by symbiont of host defense-related PCD
Jamir 2004
HopAM1-1 (Pto DC3000)
ISS
N tab Xanthi
negative regulation by symbiont of host defense-related PCD
Goel 2008
-
IDA
A thal Ws-0
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system 
P
Chang 2005
HopAM1-1 (Pto DC3000)
ISS
A thal Col-0
-
negative regulation by symbiont of host defense-related PCD
P
Jamir 2004
HopAM1-1 (Pto DC3000)
ISS
A thal Ws-0
-
Jamir 2004
HopAM1-1 (Pto DC3000)
ISS
N tab Xanthi
-
negative regulation by symbiont of host resistance gene-dependent defense response
P
Jamir 2004
-
IDA
N tab xanthi
reduces HR elicited by HopA1- RPS6 interaction
killing by symbiont of host cells 
P
Munkvold 2008
HopAM1-1 (Pto DC3000)
ISS
S cerevisiae  
-
negative regulation by symbiont of host apoptosis
P
Jamir 2004
HopAM1-1 (Pto DC3000)
ISS
S cerevisiae
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Goel 2008
HopAM1-1 (Pto DC3000)
ISS
A thal Ws-0
negative regulation of callose deposition induced by hrcC- DC3000
modulation by symbiont of host signal transduction pathway
P
Goel 2008
HopAM1-1 (Pto DC3000)
ISS
A thal Ws-0
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Goel 2008
HopAM1-1 (Pto DC3000)
ISS
A thal Ws-0
reduces callose deposition induced by hrcC- DC3000
positive regulation by symbiont of abscisic acid levels in host
GO:1990218
P
de Torres-Zabala 2007
HopAM1-1 (Pto DC3000)
ISS
A thal
ABA biosynthetic enzyme NCED3 transcripts positively regulated

 


hopAO1 (PSPTO_4722)
(RefSeq link)
GO term
GO ID
Ontology
Reference
PubMed ID
with
Evidence Code
Host ID
Host interaction
host cell  cytoplasm
C
Underwood 2007
-
IDA
A thal Col-gl1
-
protein tyrosine phosphatase activity
F
Espinosa 2003
-
IDA
-
-
Bretz 2003
-
IMP
-
-
pathogenesis
P
Espinosa 2003
-
IDA
N benth
negative regulation by symbiont of host defense-related PCD
Espinosa 2003
-
IDA
N tab xanthi
negative regulation by symbiont of host defense-related PCD
Underwood 2007
-
IDA
A thal Col-gl1
negative regulation by symbiont of PAMP-induced host innate immunity
interaction with host via protein secreted by type III secretion system 
P
Bretz 2003
-
IDA
A thal Col-0
-
protein kinase binding
F
Macho 2014
-
IPI
A thal
binds FLS2
protein kinase binding
F
Macho 2014
-
IPI
A thal
binds EFR
modulation by symbiont of host molecular function
P
Macho 2014
-
IDA
A thal
reduces elf18-induced phosphorylation of EFR
positive regulation of growth of symbiont involved in interaction with host 
P
Espinosa 2003
-
IDA
A thal Col-0
-
Bretz 2003
-
IDA
A thal Col-0
-
Espinosa 2003
-
IDA
S lyco Money maker
-
negative regulation by symbiont of host defense-related PCD
P
Espinosa 2003
-
IDA
N benth
-
Espinosa 2003
-
IDA
N tab xanthi
-
Bretz 2003
-
IDA
N tab L
-
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Bretz 2003
-
IDA
N tab L
-
negative regulation by symbiont of defense-related host reactive oxygen species production
P
Macho 2014
-
IDA
A thal
reduces flg22 and elf18 induced ROS
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
Espinosa 2003
-
IDA
N tab xanthi
reduces NtMEK2-dependent cell death
Espinosa 2003
-
IDA
N benth
reduces NtMEK2-dependent cell death
negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
Macho 2014
-
IDA
A thal
reduces elf18 induced MPK3, MPK6, MPK4/11 activation
positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway
P
Underwood 2007
-
IDA
A thal Col-gl1
upregulates MPK3 MPK6
negative regulation by symbiont of host defense-related protein level 
P
Bretz 2003
-
IDA
A thal Col-0
reduces PR1 expression
Underwood 2007
-
IDA
A thal Col-gl1
reduces PR1 PR2 PR5 HIN1-like AIG1upregulation by hrpA
modification by symbiont of host morphology or physiology
P
Munkvold 2008
-
IDA
S cerevisiae
-
negative regulation by symbiont of defense-related host cell wall callose deposition
P
Underwood 2007
-
IDA
A thal Col-gl1
negative regulation of callose deposition induced by Pto DC3000 hrpA-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Underwood 2007
-
IDA
A thal Col-gl1
-
negative regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity
P
Macho 2014
-
IDA
A thal
reduces elf18-induced phosphorylation of EFR
go to annotations for Type III effectors not found in Pto DC3000 and Pto DC3000 Type III helpers


Magdalen Lindeberg
PPI Project Coordinator
Dept Plant Pathology
Cornell University
contact